Error: ERR_UNEXPECTED (Site can't be reached) in Chrome on HTTPS

You are likely running Windows Server 2016 and have a client on Windows 10. A feature in this server OS is causing it to use HTTPS/2.

Disable HTTP/2 Protocol on Windows 10 and Windows 2016 machines.

With some browsers, you may encounter the error ERR_SPDY_PROTOCOL_ERROR when accessing a Windows 10 VADC or Windows 2016 VADC desktop.

You can prevent this error by disabling the HTTP/2 protocol on the both the server and the client computer.

1. Start the Windows Registry Editor.
2. Navigate to the registry key HKEY_LOCAL_MACHINE\System\CurrentControlSet\Services\HTTP\Parameters.
3. Add 2 new REG_DWORD values, EnableHttp2Tls and EnableHttp2Cleartext, to this registry key.
4. Set both values to 0.
5. Reboot the desktop.